Galderma Announces FDA Approval of 0.1% Differin® Gel For Over-the-Counter Acne Use

Galderma Announces FDA Approval of 0.1% Differin® Gel For Over-the-Counter Acne Use

Using a Carbon-13 NMR for quality control…

This is an auto sampling carbon NMR!

This machine can help you identify organic materials based on signals from carbon atoms. Carbon-13 nuclei have a “spin”, and this machine can read signals produced after the nuclei are subjected to a strong magnetic pulse.

This is just one of the techniques we can use to identify and test the quality of material. Unfortunately a piece of paper from a supplier saying the material is of high quality…just isn’t enough! As cosmetic chemists we have our clients’ health and skin as our responsibility, so it’s important to make sure that the material going in to our products are what they’re supposed to be, as pure and high quality as possible, and pathogen and contaminant free.

The FDA recently reported a fungal contamination of eye shadows from a small company, as well as unacceptably high levels of lead in a bentonite clay product – marketed for babies.

Sure, it’s a little bit of time and money spent on doing your own quality control….but can you put a price on your clients’ trust and health?

Yesterday I had some samples of hyaluronic acid tested. I wanted to make sure that the material was of high quality, free of heavy metal contaminants and pathogens, and was actually hyaluronic acid

I’ve heard horror stories of suppliers (and repackers) passing off other material as more expensive material. One person told me that they had received an order of product and only the top layer was what it was supposed to be! The rest of the container was just cheap filler!


There’s only one way to prevent these kinds of oversights… and that’s constance vigilance…in the words of Alastor Moody!

And it’s not just the cosmetics industry…Consumer Reports did an experiment a few years ago and found that only 20% of the fish they bought at restaurants and markets were actually the labeled species

Did some cleaning in the lab, and found this!

This is a self sealing, airless, and metered dose dispensing system. The bag doesn’t leak product when squeezed, but when the button is pressed…it dispenses the same amount of product each time (or at least close). It was designed to deliver skincare products and drugs.

Sadly the company is no longer in business and this is probably one of the last prototypes sitting around. As a testament to its storage ability I think this one is almost 9 years old!

Here’s the original press release announcing the product:

Poly-D’s MDS patented pump and valve dispensing mechanism allows for easy, one-handed dispensing of an exact amount of product with viscosities up to 50,000cps.

The vacuum-based technology means the pump forces it out of the pouch (98% of it) in a neat and clean manner, and because it is a vacuum-based technology, it works in any orientation.

The MDS valve only opens when the button is pressed and then seals tight upon release, eliminating the need for caps and closures.

It can be used as a stand-alone dispensing package or integrated into applicators or custom-designed devices.