Timolol for the treatment of Acne and Rosacea

Where? Johns Hopkins University in Baltimore, Maryland, United States

What? The researchers want to see how timolol, a medication most commonly used to treat high bood pressure or glaucoma, can affect acne or rosacea

How? Participants will apply timolol to half of their skin for 8 weeks, and then their whole face for 8 weeks

Who? Must have acne or rosacea. Can not be pregnant or bearded, and should not be using acne or rosacea medications

Contact Sabrina Alessi at 410 502 7546

Sebacia Gold-coated Microparticles and Laser Therapy for the treatment of Acne

Where? Sebacia, Inc. in Aalborg, Denmark and Geneva, Switzerland

What? The researchers want to see how well Sebacia Microparticles reduce acne. Sebacia Microparticles are gold plated silica microparticles, they are designed to penetrate the skin and lodge in areas like the sebaceous gland. A laser is then placed on the skin and the laser is selectively absorbed by the Sebacia Microparticles and converted to heat. This heat is thought to reduce the activity of the sebaceous gland

How? Participants will be evaluated every 12 weeks for 36 weeks. It’s unclear how many times the Sebacia Microparticle and laser treatment will be performed

Who? You must not have tattoos in the area with acne, you can not be pregnant. You must be eligible to receive laser treatments, or not had a laser or intense pulsed light treatment recently

Contact Mariann Wittendorff at +45 98 12 52 59 in Denmark and Silvia Ferrari at 4122 807 2777 or silvia@skinpulse.ch in Switzerland

A 4% Minocycline Foam for the treatment of Moderate-to-Severe Acne

Where? Foamix Ltd. in Arizona, Colorado, Florida, Georgia, Illinois, Indiana, Kansas, Kentucky, Louisiana, Michigan, New Jersey, New Mexico, New York, North Carolina, Ohio, Pennsylvania, Tennessee, Texas, Utah, Washington, United States

What? FMX-101 is a foam that contains 4% of the antibiotic minocycline

How? Participants will use the FMX-101 foam or a placebo for 12 weeks. After 12 weeks participants can decide to use the FMX-101 foam for an additional 40 weeks

Who? You must have moderate to severe acne, and no more than 2 nodules. You must be willing to only use the supplied cleanser (Cetaphil) and no other acne medications or treatments

Contact TKL Research at 201-587-0500

Effects of Isotretinoin combined with Omega-3 Fatty Acid Supplementation for the treatment of Acne

Where? UCLA in Los Angeles, California, United States

What? The researchers want to see the effects of concurrent use of Isotretinoin and Omega-3 fatty acid supplements. Isotretinoin is an acne drug most commonly known as Accutane.

How? Participants who are taking Isotretinoin will be provided with an Omega-3 fatty acid supplement or placebo, the participants will take the supplements twice a day for 24 weeks

Who? You must be at least 18 and beginning Isotretinoin medication soon, you can not have taken Omega-3 fatty acid supplements in the past, or dyslipidemia, blood thinners, or high blood pressure medication

Contact Gail Thames at 310-825-0453

Olumacostat Glasaretil gel designed to reduce sebum production for the treatment of Acne

Where? Dermira, Inc. in Alabama, Florida, Nevada, Texas, United States

What? Olumacostat Glasaretil is a novel, small molecule in development for the treatment of acne vulgaris that is designed to target sebum production, following topical application

How? Participants will apply the Olumacostat Glasareti gel or a placebo for 12 weeks

Who? You must have moderate to severe acne, but not nodular acne. You must not use other acne medications for at least 2 weeks, and must not have participated in another acne experiment recently. You must not have used birth control for the previous 4 months. You must not have used Isotretinoin (Accutane) in the past year

Contact Beth Zib at 650-421-7210

ELAPR002f and ELAPR002g, a cross-linked tropoelastin filler for treatment of Atrophic (Sunken) Acne Scarring

Where? Elastagen Pty Ltd in London, United Kingdom

What? Tropoelastin are the smaller components that elastin is made from, the treatment injectable is combined with hyaluronic acid. Experiments have shown that after ELAPR002 is injected, it can form into elastin and can integrate into structures of the skin.

How? Participants will receive one round of injections in their scarring of either the ELAPRoo2 filler or a saline placebo. They will then return for assessment after 2 weeks and other times for 24 weeks.

Who? You must have scarring of at least 2 cm atrophic or sunken acne scarring on both sides of the face. You must not have active acne, be pregnant, or participated in a previous clinical trial in the previous month

Contact Dr. Robert Daniels at +61 9209 4054